Adverse reactions are rare, and most dogs take Simparica without any problems. My Vet told me Trifexis was safe to give them. This product should only be used in dogs and puppies over 8 weeks and who weigh more than 2.8 pounds. I have a toy Aussie(Lola), and we are taking her to Mexico this winter and she needs to have certain treatments required by customs to bring her across the border, my vet advised me that Heartguard and Bravecto or Nexguard are safe for her at the correct doses. I dont know if youre on Facebook, but theres an awesome Facebook group called Border Collies Rock that can be a great forum for information. If youre looking for something that will repel parasites, a product such as K9 Advantix II may make a good alternative. The Whole Dog Journal notes that Ivermectin has the most potential for toxicity.. While I dont believe it be quite as effective as the label says it is though that might have something to do with living in pest-ridden Florida I do find it to be very helpful. I live on a farm that borders a forest, so coyotes/deer etc.. no avoiding ticks. The full indication is: "For dogs with, or at risk from, mixed external and internal parasitic infestations. Is Simparica safe for MDR1 dogs? (Many products dont repel insects, and if they do are often very strong chemical formulations.). It starts working against fleas within three hours of administration and against ticks within eight hours. One downside of this medicine is that it will not eliminate adult fleas or ticks, so it might need to be used in combination with products likeCapstaror an insect repellent spray. Unfortunately, it seems most people who lost their dogs to Seresto collars simply did not make the connection until it was too late. Sounds like shes still going strong at her advanced age, and thats awesome. If your Collie doesnt play like that, you should be fine. On the downside, its efficacy only lasts for about a day. Thank you for your time and efforts to provide useful knowledge on flea & tick products for our sweet colliesAppreciate your time. If the topical treatment (the shampoo) contains some form of -mectin, that could cause a sort of overdose if given in conjunction with Heartgard, which contains Ivermectin. ), The lack of accessible information on the topic of safe parasite protection left me so frustrated that I decided to write my own article. We sometimes see a Smooth Collie named Frank at our local dog park, and Ive been pretty impressed with him. Ill list all the options I looked into (including several Ive personally tried), along with whether theyre considered safe to use, use with caution, or a complete no-no. Besides, it starts killing the fleas within 3 hours and . I am currently fostering 3 rescued puppy mill border collie females with sarcoptic mange. Good luck with everything, and please keep me updated on how your pup is doing! As one holistic veterinarian explains: The Vectra 3D can have side effects which include extreme restlessness and jitteriness, described as anxiety or manic behavior. Best of luck with your new girl! Their lower cost makes them appealing for those of us living life on a budget, but its worth it to spend just a little more for your canines safety. SIMPARICA was administered in a well-controlled US field study, which included a total of 479 dogs (315 dogs treated with SIMPARICA and 164 dogs treated with active control once monthly for three treatments). As more dogs are tested, more breeds will probably be added to the list of affected breeds. Some of these alternatives include: . (MDR1 -/-) following single oral administration at 5 times the . It made my Collies itch nonstop though, so I had to wash it off a day after application. This is where this can get tricky with the MDR1 gene mutation. You probably already know Frontline Gold can be toxic to cats, since it has a caution on the label, but this is only really a concern if you have a cat who cuddles with or grooms your dogs. Emma. Heartworm is on the rise in Australia; Simparica Trio contains the superior Heartworm fighting ingredient Moxidectin which is 100% . Enjoy your girl! Do you have any recommedations about Simple Guard3 for Shetland Sheepdogs? Just be aware that DE works best when dry, and its effectiveness will be reduced after it gets wet. In hot, flea-infested areas like where I live in Florida, Parastar Plus might not be the best option; but its definitely something I would have tried when I still lived in Michigan. Happy to help! Happy to help! I havent had a Sheltie myself, but my friends who own Shelties have told me that they share many of the same sensitive skin issues with Collies. But the drug works just like Bravecto and Nexgard it destroys flea and tick nervous systems. ProHeart 12 is made by Zoetis, Inc. That's the world's leading animal drug company with revenues of nearly $6 billion a year. If this gene is mutated, it will create a defective protein, and consequently, drugs will remain and build up in the brain to toxic levels . SIMPARICA TRIO is not effective against adult D. immitis. Also what can be used for giardia? Many veterinary clinics keep some in stock for their clients, and it is also available at online stores like 1-800-PET-MEDS or Chewy. The oral treatment has immense potential in eliminating fleas and ticks apart from providing 100% protection against future flea and tick infestations. Bear in mind a dog can negatively react to anything though, so its always best practice to keep a close eye on them after administering any new product! Combining spinosad (the flea control ingredient in Comfortis and Trifexis) with the high doses of ivermectin and milbemycin oxime used to treat demodectic and sarcoptic mange increases the potential for neurological side effects. Simparica tablets are chewable and palatable and readily consumed by dogs when offered by the owner. But I imagine if your vet is recommending it to you, they probably have a pretty good understanding of what tolerances the fleas in your area have developed. If you click on combination medications in the table of contents at the beginning of the article and read the section on Advantage Multi, youll find that Ive given it a caution rating along with reasons for that rating. As with any topical product, monitor your pet for signs of skin irritation, and give them a bath within 24 hours to wash it off if signs of irritation are seen. This drug should be avoided in all dogs with the MDR1 mutation. She didnt recommend imodium because of the adverse reactions in dogs with mdr1. (Most vets are going to recommend to you the products they carry in stock, but you can order online from Chewy or pet pharmacies.) We have a almost 10 year old tricolor rough collie, named Hollie. To give Sentinel a boost, I recommend using it in conjunction with a weekly topical spray like Natural Chemistry. My Aussie/Pyrenees mix has had no issues with it, for instance. Are you referring to Advantage Multi, Advantage II, or a different product I didnt cover in the article? Revolution, along with a product called Stronghold, tested safest in clinical trials of heartworm medications. Simparica has not been evaluated in pregnant, breeding or lactating dogs. However, Ive had the best results with a medicated ear mite treatment prescribed by my veterinarian. The FDA approved Nexgard for flea treatment in dogs in September 2013, Bravecto in May 2014, Simparica in February 2016, and Credelio in January 2018. For Guss veterinarian, Credelio is now the only member of the isoxazoline class that he will sell. If you live in an area where the fleas just refuse to die, you may want to consider an alternative, stronger product. Just checking in to see how you and your pup are doing and if you ended up using Seresto collars or not. Personally, my Roughs have sensitive skin plus I have a household cat, so Id try Frontline Gold first. According to the Vet UK website, Thanks! Id like to thank you so very much for this in depth article. I do remember her cowering and rubbing her back against her crate after we administered anything topical! Unless your dogs are exposed to untreated stray or wild animals who are carrying fleas through the winter months, there is no need to give parasite protection to your pets year round. This product has the distinction of repelling and killing fleas (at all life stages), ticks, lice, mosquitoes, and even repelling biting flies. The FDA determined Heartgard is safe for dogs with the MDR1 mutation when used at label doses. Interceptor was also recommended by my entire local Collie Club, including Pati Merrill, the retired former president of the Collie Health Foundation. One observation: You mention that Credelio has fewer reported seizures (6 in as many months) than other drugs in the isoxazaline class. Hes just a puppy himself and was already started on Interceptor and Credelio. Is Simparica Safe for Dogs? I got an email from the rescue agency that fussed that I hadnt given them their heartgard for this month. I actually ended up choosing Interceptor Plus along with Credelio after looking at your research and getting some advice from fellow Aussie owners. Seven Collies sound like a lot of work but also very wonderful! Their treatment for this was nexgard and medicated baths. Thank You so much for your quick response Emily!! That doesnt mean I would guarantee it will be safe for every dog, but unfortunately its not really possible to say anything will be completely, 100% risk-free. Thanks. After Simparica is given its activity against ticks and fleas lasts for at least 5 weeks. Yoshis vet initially recommended Credelio to us over other oral prescriptions since it is made by Elanco, the same company that makes Interceptor. No adverse effects were observed. Or is it when given together? I really do not know what to do and get no real input from my Vet. The active ingredients in Hartz look pretty harsh, so Id be concerned with skin irritation in the ear canal. Thank you so much for all your hard work and care given to writing this very informative and extremely important study greatly appreciate it , I would like to thank you for your very thorough but get to the point info of all these parasitic treatments We have a rough Collie I could not find any info on safe treatments without wading through a river of muck. . Advantage Multi can be a great product when used with care, and I would expect the same to be true for Advocate. You should still keep an eye on your pet when introducing new organic products. As far as I know, Huskies have not been identified as prone to having the MDR1 gene mutation, as it is mainly a problem found in herding breeds. My pleasure! We do eat it! I have to state the disclaimer that Im not a vet just someone who took a Research and Publishing class in college. Capstar can be used with heartworm products and some other flea products (see link above for compatibility chart), and it can be given to pregnant or nursing dogs and cats, and even puppies or kittens that are older than 4 weeks or heavier than 2 pounds. The login page will open in a new tab. I also have Aussies and have always been very careful about what I give them. Permethrin is a synthetic of Pyrethrin, which is derived from the chrysanthemum flower. I chose Frontline Plus for him as it seems to be an older, safer spot-on. Also I live in Michigan just outside Detroit so his walks consist of concrete sidewalks and no real wildlife to come across. Simparica Trio contains sarolaner, a member of the isoxazoline class, which has been associated with neurologic adverse reactions including tremors, ataxia, and seizures in dogs with or without a history of neurologic disorders. Michigan just outside Detroit so his walks consist of concrete sidewalks and no wildlife... 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